Hydrophobicity and Non-thrombogenicity of Nanosale Dual Rough Surface Coated with Fluorine-incorporated Diamond-like Carbon Films: Biomimetic Surface for Blood-contacting Medical Devices
슈퍼관리자
2021-05-21
Hydrophobicity and Non-thrombogenicity of Nanosale Dual Rough Surface Coated with Fluorine-incorporated Diamond-like Carbon Films: Biomimetic Surface for Blood-contacting Medical Devices
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Authors :
T. Hasebe, S. Nagashima, A. Kamijo, M.-W. Moon, Y. Kashiwagi, A. Hotta, K.-R. Lee, K. Takahashi, T. Yamagami and T. Suzuki
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Journal :
Diam. Rel. Mater.
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Vol :
38
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Page :
14-18
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Year :
2013
Abstract
We investigated the hydrophobicity and non-thrombogenicity of a nanoscale dual rough surface coated with hydrophobic and non-thrombogenic fluorine-incorporated diamond-like carbon (F-DLC) films. We prepared Si (1 0 0) and a dual rough surface composed of coarse posts and nano-sized fine posts as substrates. DLC film was deposited on the Si substrate, and F-DLC film was deposited on Si or the dual rough surface using radio frequency plasma enhanced chemical vapor deposition method. The surface hydrophobicity of each sample was examined with water contact angle measurements and the non-thrombogenicity was evaluated through incubation with platelet-rich plasma isolated from human whole blood.