Comparison of Diamond-like Carbon-Coated, Nitinol Stents with or without Polyethylene Grycol Grafting and Uncoated Nitinol Stents in a Canine Iliac Artery Model
슈퍼관리자
2021-05-21
Comparison of Diamond-like Carbon-Coated, Nitinol Stents with or without Polyethylene Grycol Grafting and Uncoated Nitinol Stents in a Canine Iliac Artery Model
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Authors :
Jin Hyoung Kim, Ji Hoon Shin, Dong Ho Shin, Myoung-Woon Moon, Kwideok Park, Tae-Hyung Kim, Kyoung Min Shin, Yong Hyun Won, Dong Keun Han, Kwang-Ryeol Lee
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Journal :
The British Journal of Radiology
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Vol :
84
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Page :
210-215
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Year :
2011
Abstract
Objective: Neointimal hyperplasia is a major complication of endovascular stent placement with consequent in-stent restenosis or occlusion. Improvements in the biocompatibility of stent designs could reduce stent-associated thrombosis and in-stent restenosis. We hypothesised that the use of a diamond-like carbon (DLC)-coated nitinol stent or a polyethylene glycol (PEG)-DLC-coated nitinol stent could reduce the formation of neointimal hyperplasia, thereby improving stent patency with improved biocompatibility.Methods: A total of 24 stents were implanted, under general anaesthesia, into the iliac arteries of six dogs (four stents in each dog) using the carotid artery approach. The experimental study dogs were divided into three groups: the uncoated nitinol stent group (n = 8), the DLC-nitinol stent group (n = 8) and the PEG-DLC-nitinol stent group (n = 8).
Results: The mean percentage of neointimal hyperplasia was significantly less in the DLC-nitinol stent group (26.7
